The GLP-1 agonist, liraglutide, as a pharmacotherapy for obesity GLP-1 agonist to treat obesity and prevent Cardiovascular Disease: what have we achieved so far? The GLP-1 […]

Nasal Colivelin treatment ameliorates memory impairment related to Alzheimer’s disease Arctigenin effectively ameliorates memory impairment in Alzheimer’s disease model mice targeting both β-amyloid production and clearance […]

The hallmarks of cancer Revisiting the hallmarks of cancer Hallmarks of cancer: the next generation What are the hallmarks of cancer? Hallmarks of cancer: new dimensions […]

The Warburg effect: 80 years on The Warburg effect: how does it benefit cancer cells? The Warburg effect in 2012 We need to talk about the […]

Reversal of obesity by targeted ablation of adipose tissue Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ Reversal of obesity-related […]

Immunoregulatory functions of mTOR inhibition Dissecting the role of mTOR: lessons from mTOR inhibitors Updates of mTOR inhibitors mTOR inhibitors: an overview The pharmacology of mTOR […]

Molecular mechanism of nrf2 activation by oxidative stress The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress Natural Nrf2 activators in diabetes […]

AMPK activation: a therapeutic target for type 2 diabetes? AMPK activators–potential therapeutics for metabolic and other diseases AMPK activation, a preventive therapeutic target in the transition […]

SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages Sirt 1 activator inhibits the AGE-induced apoptosis and p53 acetylation in human vascular endothelial cells […]