February 5, 2021

INSULIN & AGING

insulin & aging Reduced Circulating Insulin Enhances Insulin Sensitivity and Extends Lifespan The causal relationships between insulin levels, insulin resistance, and longevity are not fully elucidated. […]
February 8, 2021

INSULIN & MTOR

mTor‐dependent stimulation of the association of eIF4G and eIF3 by insulin insulin signalling to mTor mediated by the Akt/PKB substrate PRAS40 The role of mammalian target […]
February 8, 2021

EXCITOXICITY & THE BRAIN

Monocyte chemoattractant protein-1 and macrophage inflammatory protein-2 are involved in both excitotoxin-induced neurodegeneration and regeneration excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator […]
February 9, 2021

POLYAMINES & THEIR EFFECT ON BRAIN (NMDA, DEPRESSION, SUICIDE RISK)

brain polyamine levels are altered in Alzheimer’s disease polyamine transport, accumulation, and release in brain The polyamine transporter Slc18b1(VPAT) is important for both short and long […]
February 11, 2021

PREVENTING SKIN AGING

skin aging skin aging skin aging Fifty years of skin aging Molecular mechanisms of skin aging: state of the art Retinoids in the treatment of skin […]
February 11, 2021

ANTI WRINKLE AGENTS

Evaluation of Anti-wrinkle effects of a novel cosmetic containing niacinamide Anti-wrinkle and anti-Inflammatory effects of active garlic components and the inhibition of MMPs via NF-κB signaling […]
February 11, 2021

ANTI AGING

anti-aging effect of astragalosides and its mechanism of action. aging: The Reality: “anti-aging” Is an Oxymoron The war on “anti-aging medicine” Role of antioxidants in the […]
February 11, 2021

MITOCHONDRIAL UNCOUPLING

The biology of Mitochondrial Uncoupling proteins The Mitochondrial Uncoupling-protein homologues Mitochondrial Uncoupling proteins—what is their physiological role? Superoxide activates Mitochondrial Uncoupling proteins The Mitochondrial Uncoupling proteins […]
February 11, 2021

HORMESIS

Hormesis defined Radiation Hormesis Hormesis in aging Hormesis: why it is important to toxicology and toxicologists Hormesis and medicine Hormesis with ionizing radiation Hormesis as a […]